Nonlinear stability of two dusty magnetic liquids surrounded via a cylindrical surface: impact of mass and heat spread.

The current article examines a nonlinear axisymmetric streaming flow obeying the Rivlin-Ericksen viscoelastic model and overloaded by suspended dust particles. The fluids are separated by an infinite vertical cylindrical interface. A uniform axial magnetic field as well as mass and heat transmission (MHT) act everywhere the cylindrical flows. For the sake of simplicity, the viscous potential theory (VPT) is adopted to ease the analysis. The study finds its significance in wastewater treatment, petroleum transport as well as various practical engineering applications. The methodology of the nonlinear approach is conditional primarily on utilizing the linear fundamental equations of motion along with the appropriate nonlinear applicable boundary conditions (BCs). A dimensionless procedure reveals a group of physical dimensionless numerals. The linear stability requirements are estimated by means of the Routh-Hurwitz statement. The application of Taylor's theory with the multiple time scales provides a Ginzburg-Landau equation, which regulates the nonlinear stability criterion. Therefore, the theoretical nonlinear stability standards are determined. A collection of graphs is drawn throughout the linear as well as the nonlinear approaches. In light of the Homotopy perturbation method (HPM), an estimated uniform solution to the surface displacement is anticipated. This solution is verified by means of a numerical approach. The influence of different natural factors on the stability configuration is addressed. When the density number of the suspended inner dust particles is less than the density number of the suspended outer dust particles, and vice versa, it is found that the structure is reflected to be stable. Furthermore, as the pure outer viscosity of the liquid increases, the stable range contracts, this means that this parameter has a destabilizing effect. Additionally, the magnetic field and the transfer of heat don't affect the nature of viscoelasticity.

Delving into the death signaling pathway of hemp oil and gamma radiation in solid tumor bearing mice.

Many studies reported the diverse therapeutic potential of essential oils. They have a crucial role in cancer prevention and treatment. Antioxidant, antimutagenic, and antiproliferative are mechanisms involved. Also, essential oils may enhance immune function and surveillance, induce enzymes, enhance detoxification, and modulate multidrug resistance. Hemp oil, obtained from Cannabis sativaL. seeds, is known for its health-enhancing properties and bioactivity. Adult female Swiss albino mice were injected with viable Ehrlich ascites carcinoma cells (2.5 × 106 cells/mouse), and then administered with hemp oil (20 mg/kg) daily for 10 consecutive days pre-, and then 10 days post-exposure to 6 Gy whole-body gamma irradiation. Hemp oil significantly increased Beclin1, VMP1, LC3, cytochrome c, and Bax. More interestingly, Hemp oil showed a significant decrease in Bcl2 and P13k either alone or in combination with γ radiation. Finally, this study documented the possible role of hemp oil in inducing two cell death types, autophagy and apoptosis, as it may be applied as an adjuvant in cancer treatment.

Biological evaluation of pyrazinamide liposomes for treatment of Mycobacterium tuberculosis.

Pyrazinamide liposomes were prepared employing the phospholipid molar ratios; dipalmitoyl phosphatidyl choline (7):cholesterol (2) neutral and dipalmitoyl phosphatidyl choline (7):cholesterol (2):dicetyl phosphate (1) negatively charged. Swelling at 52 degrees C led to higher trapping efficiencies. An optimum sterilizing dose of 25 kGy was exhibited by gamma (gamma)-irradiation. Neutral pyrazinamide liposomes (7:2), swollen for 24 h, were employed in biological evaluation for treatment of mice infected by Mycobacterium tuberculosis. Liposomal pyrazinamide could effect highly significant reduction in bacterial counts (colony forming units/g lung), 10, 20 and 30 days after the last treatment dose. Histopathological examination of mice lungs showed highest severity of infection in drug-free liposomes (control) group > pyrazinamide liposomes > free pyrazinamide 6 days/week. The results indicate high therapeutic efficacy of pyrazinamide liposomes, injected twice weekly, in treatment of M. tuberculosis in mice.